Australia - CSIRO PhD Studentships in the field of Quantitative Genetics / Genomics, Bioinformatics and Systems Biology

October 9th, 2007

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There are 3 PhD positions open at the JM Rendel laboratories, Rockhampton in the Division of Livestock Industries, Commonwealth Scientific and Industrial Research Organisation (CSIRO), Australia. These 3 PhD positions relate to scientific research projects in the area of Quantitative genetics/genomics, Bioinformatics and Systems Biology and are funded by the Office of the Chief Executive (OCE) of CSIRO, CSIRO Livestock Industries (CLI) postgraduate studentship program and Beef CRC for Genetic Technologies’ studentship awards. Students will be trained in research projects under joint supervision with a University. The division of CLI has a well established PhD training programme and there are currently around 70 doctoral and masters students within CLI.

OCE PROJECT 1: Genetic Improvement using SNP Genotyping Arrays in Livestock
This project is based on prediction of molecular (SNP) breeding values and comparison of genetic improvement/economic responses from SNP panel versus traditional selection methods in animals. Computer simulations will be used but the developed prediction methods will be tested on SNP Chip data from sheep parasite resistance whole genome scan experiments. The successful candidate will be enrolled at the University of New England (UNE), Armidale. He/She will be supervised by Dr Haja Kadarmideen at CSIRO Rockhampton and co-supervised by Prof. Julius van der Werf at UNE, Armidale.

Relevant project information and application forms can be found at CSIRO Careers online website. Applications close by October 31, 2007.

CLI PROJECT 2: Design and Power of Genetical Genomics (eQTL) Mapping
This project will investigate statistical methods, design and power of the genetical genomics experiments or expression Quantitative Trait Loci (eQTL) mapping methods. Research is computer based however opportunities exist to work on sheep parasite resistance and beef CRC cattle experiments. The successful candidate will be enrolled at the University of Sydney (USYD), Sydney. He/She will be supervised by Dr Haja Kadarmideen at CSIRO Rockhampton and co-supervised by Assoc. Prof. Peter Thomson at USYD, Camden.

Relevant project information and application forms can be found on CLI website on or after October 6, 2007.
Applications close by November 4, 2007.

BEEF CRC PROJECT 3: Cattle Fertility Gene Discovery by Integrative Genomics
This is a gene discovery project of Beef CRC Program 4 for female reproductive performance (age at puberty and post-partum re-conception success) in tropical beef cattle. The project will eventually develop a commercial DNA-based test that cattle producers can use. The PhD project is based on specific part of this large project which is to evaluate different filtering(editing) methods in analysing SNP array data and investigate advanced statistical genetic methods including genome-wide epistasis (heat mapping), random models and breed admixture mapping. The student will be enrolled at the University of New England (UNE) in Armidale or University of Queensland in Brisbane.

Relevant project information and application forms can be found at Beef CRC postgraduate project section.
Applications close by October 31, 2007.

GENERAL INFORMATION
Availability of SNP Chips and whole genome-wide association tests mark the revolutions in gene discovery for many complex traits. These studies are increasingly merged with high throughput transcriptomics experiments (genetical genomics). The candidate will work with an internationally recognised team of scientists in this area of research both within CSIRO and the university, with the access to state-of-the-art experimental and computational facilities and large genomic (SNP) and microarray gene expression databases.

All successful students will be physically based in CSIRO Rockhampton but travel frequently to respective universities for course work and/or training. Students will have close supervision and support from geneticists on site. Interested applicants must apply online using the appropriate application forms, the procedures and eligibility conditions that are available at the corresponding websites for each award. Students may apply for more than scholarship.

Eligibility and Payment
For ALL studentships, a high quality Honours or Masters degree or similar in the field of (Bio)statistics or genetics or computational sciences or animal/plant genomics/breeding or Bioinformatics or Systems Biology or similar field is required. Experience in computer programming knowledge and use of statistical analysis software is desirable. OCE PhD Project 1 is open to international applicants where as CLI and Beef CRC PhD projects (projects 2 and 3), Australian citizenship or residency are preferred. PhD scholarship is worth around AUS $30,000 per year plus benefits.

For all PhD positions, students will be selected from a pool of eligible applicants through a competitive selection process but for informal enquiries and expression of interest, please contact:

Dr Haja Kadarmideen
Principal Research Scientist and Group Leader
Computational and Systems Biology Stream
CSIRO Livestock Industries
JM Rendel Laboratory
Ibis Ave, Rockhampton QLD 4701
AUSTRALIA
Phone: + 61 7 4923 8266
Fax: + 61 7 4923 8222
Email: Haja.Kadarmideen@csiro.au
Web: www.csiro.au/li

Additional contact for OCE PROJECT 1:
Professor Julius vam der Werf
School of Rural Science and Agriculture
University of New England
Armidale NSW 2350
AUSTRALIA
Phone: +61 2 6773 2092
Fax: +61 2 6773 3275
Email: jvanderw@une.edu.au
Web: www.une.edu.au/ansc/genetics/

Additonal contact for CLI PROJECT 2:
Associate Professor Peter Thomson
Centre for Advanced Technologies in Animal Genetics and Reproduction (ReproGen)
Faculty of Veterinary Science, University of Sydney
PMB 3 (425 Werombi Road), Camden NSW 2570,
AUSTRALIA
Phone +61 2 9351 1654
Fax: +61 2 9351 1693
Email: PeterT@camden.usyd.edu.au
Web: www.vetsci.usyd.edu.au/reprogen/

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